Alzheimer's Cure: Great News

Shar McBee
July 15, 2022

Shar McBee

Leadership with a Twist of Yoga

There is fantastic news about an Alzheimer’s cure.  Do you remember Dr. Dale Bredesen - the doctor that I have been trying to help?   His work just got fantastic news.

The cognitive scores in over 80% of patients improved significantly.  This new study was published in the Journal of Alzheimer’s Disease1. 

Basically, this is what happened:  They stopped looking for a single drug to cure it.

Instead, the doctors evaluated inflammation; deficiencies of nutrients, hormones and growth factors;  gut and oral microbiomes; leaky gut; metabolic status; sleep apnea; genetic factors such as a tendency to blood clotting; vascular abnormalities; specific pathogens and toxins; and other potential contributory factors. 

They identified root causes, which were different from patient to patient.  Each patient (age 50 - 76)  was then put on a personalized plan for nine months.

The results:    unprecedent improvements, including some patients who increased their cognitive scores from the dementia range to normal.

Please share this with anyone you know who is hoping for an Alzheimer’s cure.  If you’d like to read the press release about this, click here.   For more details, read on:  

Brain MRI scans from all participants underwent regional volume analyses by computer, and documented improvements in both grey matter volume and hippocampal volume. Typical patients with MCI or dementia undergo atrophy of the brain’s grey matter (where neurons reside) of 2.2% per year, but the study patients increased their grey matter volume by 0.3%. Hippocampal atrophy rates were improved by 63%.

Lead author Dr. Kat Toups noted, “I have been the Principal Investigator on more than 20 long-term clinical trials for patients with MCI and dementia where the benchmark for success was merely a slowing in cognitive decline. This trial is the first to show actual improvement in multiple domains of functioning, as well as improvements in MRI brain scans.”

This precision medicine method -- a personalized treatment that targets the factors contributing to disease -- has been used successfully in cancer treatment and has been garnering increasing interest from the neurodegenerative disease community. Central to this more complex therapy is digital health: the brain training was developed by Posit Science, the on-line cognitive assessments used were developed by CNS Vital Signs, the MRI volumetrics developed by Brainreader and CorTechs, and the evaluation and treatment algorithm, dubbed ReCODE, was developed by Apollo Health (which was not directly involved in this trial) in collaboration with Bredesen.

Senior author of the study, Prof. Dale Bredesen, said, “We believe that the future of medicine, for treatment of complex chronic conditions such as Alzheimer’s, cancer, and cardiovascular disease, lies not in simplistic, single-drug medicine but rather in larger data sets and precision medicine protocols such as the one used in this trial.”

The findings of the trial support earlier published results, which described case studies for 100 patients in which cognitive decline associated with Alzheimer’s and pre-Alzheimer’s was reversed, and pave the way for a larger, randomized controlled trial, which is set to begin later this year at sites in Miami, Cleveland, Nashville, Sacramento, and the San Francisco Bay Area.

The article will be published in the print issue of the Journal of Alzheimer’s Disease Volume 88 Issue 4.

For information about Dr. Bredesen, click here.  His website has a list of  practitioners who have been trained in his method.  An internationally recognized expert in the mechanisms of neurodegenerative diseases, Dr. Dale Bredesen's career has been guided by a simple idea: that Alzheimer's as we know it is not just preventable, but reversible.

Dr. Bredesen earned his MD from Duke University Medical Center and served as Chief Resident in Neurology at the University of California, San Francisco (UCSF), before joining Nobel laureate Stanley Prusiner's laboratory at UCSF as an NIH Postdoctoral Fellow. He held faculty positions at UCSF, UCLA, and the University of California, San Diego. Dr. Bredesen also directed the Program on Aging at the Burnham Institute before joining the Buck Institute in 1998 as founding President and CEO.


Shar McBee

Want Shar McBee for your next event?

Find out more information, including fees and availability.
Find Out More
Keep Reading
Robert Rauch (University of Maryland Regent) on the Joy of Leadership Podcast
Shar McBee
Shar McBee
September 07, 2022
Welcome to the Joy of leadership Podcast onKMozartbrought to you ...
Suze Orman on the Joy of Leadership Podcast
Shar McBee
Shar McBee
August 21, 2022
Welcome to the Joy of Leadership Podcast on KMozart brought to you by Cobblestone Wine. I am ...
Phylicia Rashad on the Joy of Leadership Podcast
Shar McBee
Shar McBee
July 29, 2022
Welcome to the Joy of Leadership Podcast onKMozartbrought to you byCobblestone Wine.I’m ...
Robert Rauch (University of Maryland Regent) on the Joy of Leadership Podcast
Welcome to the Joy of leadership Podcast onKMozartbrought to you byCobblestone Wine.I am your host Shar McBee.In a moment you will meet our guest Bob Rauch, a Regent at the University of Maryland. But first, today’s leadership secret: Enthusiasm. Enthusiasm enables you to inspire cooperation. It warms the heart. When you are honestly...
Read More
Suze Orman on the Joy of Leadership Podcast
Welcome to the Joy of Leadership Podcast on KMozart brought to you by Cobblestone Wine. I am your host Shar McBee. In a moment you will meet our guest Suze Orman, who is undeniably America's most recognized expert on personal finance. First, we begin with today’s leadership secret: Dharma. Dharma is a Sanskrit word that loosely means...
Read More
Phylicia Rashad on the Joy of Leadership Podcast
Welcome to the Joy of Leadership Podcast onKMozartbrought to you byCobblestone Wine.I’m your host Shar McBee. Our guest, Phylicia Rashad, is a director, a star on television and Broadway, and now the new Dean of the College of Fine Arts at Howard University. You can listen on KMozart, read it below, or catch it on You Tube. It is als...
Read More
New Joy of Leadership Podcast on KMozart
Welcome to the Joy of Leadership Podcast onKMozartbrought to you byCobblestone Wine. I am your host Shar McBee. Our guest is an Academy Award winning movie producer at Walt Disney Animation, Osnat Shurer. First, we begin with today’s leadership secret: To lead is to connect.” When people feel included, they will support you. When th...
Read More
Osnat Shurer on the Joy of Leadership Podcast on KMozart
Welcome to the Joy of Leadership Podcast onKMozartbrought to you byCobblestone Wine. I am your host Shar McBee. Our guest is an Academy Award winning movie producer at Walt Disney Animation, Osnat Shurer. You can listen onKMozart,read it below, or catch it onYou Tube. It is also available onApple Po...
Read More
Alzheimer's Cure: Great News
There is fantastic news about an Alzheimer’s cure. Do you remember Dr. Dale Bredesen - the doctor that I have been trying to help? His work just got fantastic news. The cognitive scores in over 80% of patients improved significantly. This new study was published in the Journal of Alzheimer’s Disease1. Basically, this is what happened...
Read More
Leadership Training: Change Your Mind
Leadership training is successful when it is seen as an evolving situation. What we were so sure of in the past, may not be true today. If you can change your mind about people, you'll be able to accomplish what you want.A woman in a cafe left her table for a few moments and returned to discover a hobo eating her meal. She sat down, ...
Read More
CNN Business: Managers in a Pressure Cooker?
Jeanne Sahadi wrote this thoughtful article for CNN business: Managers have been living in a pressure cooker. Many have had it. Inspire your team. Deliver results. Keep costs under control. Those have always been top responsibilities for leaders and managers at work. But their job duties have grown more time-consuming and complex tha...
Read More
Nourishment: Your Key to Success?
Providing nourishment is an essential ingredient in our Joy of Leadership trainings in Los Angeles. About 5,000 people showed up at a seminar I was organizing. Many more than we expected. As the number of people increased, the ushers became overwhelmed and were not doing a good job of seating them quickly and courteously. The...
Read More
Dharma
An important concept from yoga that will be beneficial to you in leadership is dharma. The following is an excerpt from the book, Leadership with a Twist of Yoga. Dharma loosely means "to do the right thing." People often ask, "What is my great work?" If you do the work in front of you greatly, it will lead you to your great work. Dharma is abou...
Read More